PEAK PERFORMANCEDays to result

Glymphatic System Enhancement

Boost immune function through sleep

Problem it solves

Suboptimal health habits undermine energy, performance, and longevity; this framework provides specific evidence-based practices to build a sustainable physical and mental health foundation.

Best for

Individuals looking to enhance their immune function and reduce inflammation

Not ideal for

Those with underlying medical conditions should consult a doctor before attempting

Overview

Why this framework exists

The glymphatic system is a recently discovered system that clears waste from the brain during sleep. Enhancing this system through elevated feet during sleep can improve immune function and reduce inflammation. This framework provides a simple and effective way to boost the immune system and reduce the risk of illness.

Core principles

3 total
  1. The glymphatic system is essential for clearing waste from the brain during sleep.
  2. Elevating the feet during sleep can enhance the glymphatic system and improve immune function.
  3. Reducing inflammation is crucial for overall health and well-being.

Steps

2 steps
  1. Elevate Your Feet During Sleep
    Elevate your feet by 12 degrees using a rolled pillow or two pillows under your feet to enhance the glymphatic system.
    Pro tipTry to make this a habit to see consistent results.
    WarningIf you have any underlying medical conditions, consult a doctor before attempting.
  2. Improve Sleep Quality
    Improve sleep quality by establishing a consistent sleep schedule, avoiding caffeine and electronics before bedtime, and creating a relaxing sleep environment.
    Pro tipTry to avoid screens for at least an hour before bedtime.
    WarningAvoid stimulating activities before bedtime.

Checklist

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Examples

1 cases
Example 1

A person with a weakened immune system tries the glymphatic system enhancement technique and sees an improvement in their overall health and well-being.

OutcomeThe person experiences reduced inflammation and improved immune function.

Common mistakes

2 traps
Not Elevating Feet Correctly
Not elevating the feet correctly can reduce the effectiveness of the glymphatic system enhancement.
Not Improving Sleep Quality
Not improving sleep quality can reduce the effectiveness of the glymphatic system enhancement.

Origin story

How this framework came to be

The glymphatic system was first discovered in 2012, and since then, research has shown its importance in clearing waste from the brain and improving immune function. Andrew Huberman discusses the importance of this system and how to enhance it through simple techniques.

Source

Traced to primary
Source · PODCAST
Using Your Nervous System to Enhance Your Immune System | Huberman Lab Essentials
Andrew Huberman · 2025
Open source →