PEAK PERFORMANCEWeeks to result

The Low and Slow Framework

Start low, go slow

Problem it solves

low and slow

Best for

Individuals using kratom or opioids for pain relief or mood elevation

Not ideal for

Individuals with a history of substance abuse or those who are prone to addiction

Overview

Why this framework exists

The Low and Slow Framework is a approach to using kratom or opioids that involves starting with a low dose and gradually increasing it as needed. This framework is based on the idea that it is better to start with a low dose and adjust as needed, rather than starting with a high dose and risking adverse effects. The framework also emphasizes the importance of being aware of the potential for tolerance and dependence, and taking steps to minimize these risks.

Core principles

3 total
  1. Start with a low dose and gradually increase as needed
  2. Be aware of the potential for tolerance and dependence
  3. Take steps to minimize the risks of adverse effects

Steps

3 steps
  1. Start with a low dose
    Begin with a low dose of kratom or opioids and gradually increase as needed. This will help to minimize the risks of adverse effects and allow you to adjust to the substance.
    Pro tipKeep a journal to track your dosage and effects
    WarningBe aware of the potential for tolerance and dependence
  2. Monitor your effects
    Pay attention to how you are feeling and adjust your dosage accordingly. If you are experiencing adverse effects, reduce your dosage or seek medical attention.
    Pro tipKeep a journal to track your effects
    WarningBe aware of the potential for overdose
  3. Take steps to minimize risks
    Take steps to minimize the risks of adverse effects, such as using a low dose, avoiding combination with other substances, and seeking medical attention if necessary.
    Pro tipConsult with a medical professional before using kratom or opioids
    WarningBe aware of the potential for interaction with other substances

Checklist

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Examples

2 cases
Successful use of kratom for pain relief

An individual uses kratom for pain relief, starting with a low dose and gradually increasing as needed. They monitor their effects and adjust their dosage accordingly, minimizing the risks of adverse effects.

OutcomeThe individual experiences effective pain relief with minimal adverse effects.
Unsuccessful use of opioids for mood elevation

An individual uses opioids for mood elevation, starting with a high dose and not monitoring their effects. They experience adverse effects, including dependence and overdose.

OutcomeThe individual experiences severe adverse effects and seeks medical attention.

Common mistakes

3 traps
Starting with too high a dose
Starting with too high a dose can increase the risk of adverse effects and dependence.
Not monitoring effects
Not monitoring effects can lead to unintended consequences, such as overdose or dependence.
Not taking steps to minimize risks
Not taking steps to minimize risks can increase the likelihood of adverse effects and dependence.

Origin story

How this framework came to be

The Low and Slow Framework was developed based on the experiences of individuals who have used kratom or opioids for pain relief or mood elevation. It is based on the idea that it is better to start with a low dose and adjust as needed, rather than starting with a high dose and risking adverse effects.

Source

Traced to primary
Source · PODCAST
Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy
Andrew Huberman · 2025
Open source →