PEAK PERFORMANCEMonths to result

The PCOS Diagnosis Framework

Accurate diagnosis for PCOS

Problem it solves

unproductive meetings that waste collective time

Best for

Women with irregular periods, high testosterone, or PCOS-like symptoms

Not ideal for

Women without symptoms or with other underlying health conditions

Overview

Why this framework exists

The PCOS Diagnosis Framework is a structured approach to diagnosing Polycystic Ovary Syndrome (PCOS) in women. It involves meeting two out of three criteria: symptoms of high testosterone, ovulation dysfunction, and PCOS-looking ovaries on ultrasound. The framework also considers other factors such as mood disorders, weight gain, and eating disorders.

Core principles

3 total
  1. A comprehensive diagnosis of PCOS requires a combination of clinical and ultrasound findings.
  2. PCOS is a spectrum disorder with four different phenotypes, making diagnosis challenging.
  3. Early diagnosis and treatment of PCOS can improve fertility and overall health outcomes.

Steps

3 steps
  1. Identify Symptoms
    Identify symptoms of high testosterone, such as facial hair, body hair, acne, and male pattern hair thinning.
    Pro tipConsider other factors such as mood disorders, weight gain, and eating disorders.
    WarningDo not rely solely on hormone levels for diagnosis.
  2. Conduct Ultrasound
    Perform a pelvic ultrasound to look for PCOS-looking ovaries, which are characterized by 20 or more follicles.
    Pro tipUse ultrasound findings in combination with clinical symptoms for accurate diagnosis.
    WarningDo not confuse PCOS with other conditions that may have similar ultrasound findings.
  3. Evaluate Hormone Levels
    Assess hormone levels, including testosterone and AMH, to support diagnosis.
    Pro tipConsider the patient's medical history and other factors that may influence hormone levels.
    WarningDo not rely solely on hormone levels for diagnosis.

Checklist

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Examples

1 cases
Case Study 1

A 25-year-old woman presents with irregular periods, acne, and hair thinning. Ultrasound reveals PCOS-looking ovaries, and hormone panels show elevated testosterone levels.

OutcomeThe patient is diagnosed with PCOS and begins treatment, including hormone regulation and lifestyle changes.

Common mistakes

2 traps
Misdiagnosis
Failing to consider the full range of PCOS symptoms and relying solely on hormone levels or ultrasound findings can lead to misdiagnosis.
Delayed Diagnosis
Failing to diagnose PCOS in a timely manner can lead to delayed treatment and poor health outcomes.

Origin story

How this framework came to be

The framework was developed based on the clinical experience of Dr. Thaïs Aliabadi, who has spent 25 years working with PCOS patients. She emphasizes the importance of a comprehensive approach to diagnosis, including pelvic ultrasounds and hormone panels.

Source

Traced to primary
Source · PODCAST
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
Andrew Huberman · 2025
Open source →