PEAK PERFORMANCEMonths to result

Neuromodulator Access Model

Accessing dopamine, epinephrine, and norepinephrine

Problem it solves

Suboptimal health habits undermine energy, performance, and longevity; this framework provides specific evidence-based practices to build a sustainable physical and mental health foundation.

Best for

Individuals with ADHD seeking to understand the role of neuromodulators in their condition

Not ideal for

Those without a basic understanding of neuroscience or ADHD

Overview

Why this framework exists

The Neuromodulator Access Model proposes that individuals with ADHD have a higher threshold for accessing dopamine, epinephrine, and norepinephrine, leading to difficulties in focus and attention. This model suggests that medication and other interventions can help increase access to these neuromodulators, improving symptoms of ADHD.

Core principles

3 total
  1. Dopamine, epinephrine, and norepinephrine play a crucial role in attention and focus.
  2. Individuals with ADHD have a higher threshold for accessing these neuromodulators.
  3. Medication and other interventions can help increase access to these neuromodulators, improving symptoms of ADHD.

Steps

3 steps
  1. Understanding the Role of Neuromodulators in ADHD
    Learn about the basics of dopamine, epinephrine, and norepinephrine and their role in attention and focus.
    Pro tipConsult with a healthcare professional to determine the best course of treatment for your specific needs.
    WarningDo not attempt to self-medicate or alter your treatment plan without consulting a healthcare professional.
  2. Assessing Your Current Level of Neuromodulator Access
    Work with a healthcare professional to assess your current level of neuromodulator access and determine the best course of treatment.
    Pro tipKeep a symptom journal to track your progress and identify patterns.
    WarningBe patient and persistent, as finding the right treatment plan may take time.
  3. Exploring Medication Options
    Research and discuss different medication options with your healthcare provider, including their potential benefits and risks.
    Pro tipAsk about the potential for side effects and how to manage them.
    WarningDo not stop taking medication without consulting your healthcare provider.

Checklist

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Examples

1 cases
Case Study: Amphetamine-Induced Psychosis

A 40-year-old male with ADHD was prescribed amphetamine, which led to a psychotic episode. Despite the severity of the episode, the individual continued to seek out the medication due to the perceived benefits.

OutcomeThe individual was hospitalized and required intensive treatment to manage the psychosis.

Common mistakes

2 traps
Not Consulting a Healthcare Professional
Failing to consult a healthcare professional can lead to misdiagnosis, ineffective treatment, and potential harm.
Not Monitoring Side Effects
Failing to monitor side effects can lead to serious health consequences, including amphetamine-induced psychosis.

Origin story

How this framework came to be

The model is based on the idea that ADHD is not just a matter of poor focus, but rather a complex interplay between neurotransmitters and brain function. By understanding how neuromodulators contribute to ADHD, individuals can better manage their symptoms and improve their overall well-being.

Source

Traced to primary
Source · PODCAST
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse
Andrew Huberman · 2025
Open source →