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Antonio Damasio

somatic-marker hypothesis.

António Damásio directs the Brain and Creativity Institute at the University of Southern California. His clinical work with patients with prefrontal lesions revealed that damage to emotion-processing circuits devastates real-world decision-making despite intact reasoning, underpinning the somatic marker hypothesis. His books, including Descartes' Error, brought this framework to broad academic and popular audiences.

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Last updated
10 May 2026
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